CAS 148553-50-8 PREGABALIN;(R)-Pregabalin
Product Details
CAS 148553-50-8 Pregabalin (Lyrica), an analog of GABA that is related to gabapentin, has been extensively studied in the treatment of GAD, fibromyalgia, neuropathic pain, and partial complex seizures.It appears to act even more selectively on the a2-? subunit of calcium channels found in brain than does gabapentin. Pregabalin received FDA approval in late 2004 for use in treating neuropathic pain and epilepsy. In 2008, it became the first drug approved for the treatment of fibromyalgia.Even though prcgabalin reccived approval for the treatment of GAD in the European Union in 2006, the FDA has not approvedpregabalin for GAD in the United States as of this writing.With the consistent efficacy in clinical trials and the known safety of pregabalin in clinical expericnce, it is not completely clear what has held up approval of prcgabalin for GAD.There was reported concern of the risk-benefit ratio for the drug,given the hepatotoxicity seen in micc, but this has not proven to be a problem postrelease in humans. Pregabalin is categorized as an anticonvulsant and analgesic. The drug is under re-review currently by the FDA. Pregabalin has a potential for abuse and misuse. Pregabalin is regulated as a Schedule V compound in the United States.
Company Product
Related Product
New Products
- Rolls-Royce automobile air conditioning compressors BMW Alpina B7L xDrive Base 4.4L 2011-2
- 10pa15 / 10PA15L car ac compressors factory directly sale Audi Citroen
- N-(tert-Butoxycarbonyl)-4-piperidone CAS 79099-07-three
- 4\\\'-Methylpropiophenone CAS 5337-93-nine
- 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one CAS 52190-28-0
- sodium,2-methyl-3-phenyloxirane-2-carboxylic acid CAS 5449-12-7
- BMK methyl glycidate CAS 80532-66-7
- 2-(2-Chlorophenyl)-2-nitrocyclohexanone CAS 2079878-75-2
- 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE CAS 288573-56-8
- (4-Fluoro-phenyl)-piperidin-4-yl-amine dihydrochloride CAS 1193389-70-6
- Ethyl 2-phenylacetoacetate CAS5413-5-8
- 2-BROMO-1-PHENYL-PENTAN-1-ONE CAS49851-31-2
- PMK ethyl glycidate CAS 28578-16-7
- China pesticides agrochemicals Glyphosate SL herbicides
- wrought iron leaves and flowers for gate fence staircase railing handrails balustrades