- Company : Xi'an ChinWon Biotech Inc.
- Region : Shaanxi , China
- Category : Agriculture > Plant Extract
- Specification : Active ingredient: 1-Deoxynojirimycin English Name: 1-Deoxynojirimycin Short Name: 1-DNJ, DNJ Molecular Formula: C6H13NO4 Molecular Weight: 163.17 CAS NO.: 19130-96-2 Appearace: yellowish green or pale yellowish brown fine powder Assay: 1%,2% HPLC
- Contact Person : Bonnie.Ype|||
- Telephone :
- Website : www.chinwon.net
- Email : [email protected]
- Update : Apr/02/2016
Product Details
The benefits of Mulberry leaf extracts are related to a compound called 1-deoxynojirimycin (DNJ) and some of its derivatives, which are reported to inhibit the activity of a carbohydrate digesting enzyme called alpha-glucosidase. By slowing or stopping this enzyme, the digestion of starch and oligosaccharides is slowed, which suppresses blood glucose spikes after eating. Writing in the Journal of Functional Foods , Korean researchers from Ewha Woman’s University and the Seoul National University of Science and Technology noted that intakes of 2.5 or 5 grams of mulberry leaf led to lower blood glucose levels after a ingesting a maltose solution. “Ingestion of mulberry leaf aqueous extract containing 0.36% DNJ effectively reduced hyperglycemia after a 75 g maltose challenge in healthy subjects from the initial measurement at 0–180 min,” wrote the researchers. “The effective doses were 2.5–5 g of mulberry leaf aqueous extract, which correspond to 9–18 mg of DNJ, respectively.” Study details The Seoul-based researchers recruited 50 healthy people to participate in their randomized, double-blind, placebo-controlled trial. Subjects were randomly assigned to one of five groups: Four groups received a maltose powder drink with 0, 1.25, 2.5, or 5 grams of the mulberry leaf extract. The fifth group consumed a beverage with 5 grams of the mulberry leaf extract 30 minutes before drinking the maltose solution.